His publicist says he was hospitalized "a few days ago in Vegas after a Mobb Deep performance for complications caused by a sickle cell anemia crisis. As most of his fans know, Prodigy battled the disease since birth."
The publicist added ... "the exact cause of death has not been determined."
Prodigy was in Vegas over the weekend performing with the Art of Rap tour ... with Ghostface Killah, Onyx, KRS-One, and Ice-T ... Mobb Deep performed Saturday night. See video below
Prodigy and his partner, Havoc, formed Mobb Deep in NYC in the early '90s. Their biggest hits include "Quiet Storm" and "Shook Ones."
He was 42.